RSPO2 Polyclonal Antibody, 100ul Protein Post-translational Modification This protein shares strong similarity

This protein shares strong similarity with DNA replication factor C (RFC)| and can form a complex with RFCs

Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A

This gene and the gene encoding defensin

it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer

RSPO2 Polyclonal Antibody, 100ul Protein Post-translational Modification This protein shares strong similarityThis gene encodes a member of the R spondin family of proteins. These proteins are secreted ligands of leucine rich repeat containing G protein coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.