EpoR(Phospho Tyr426) Polyclonal Antibody, 20ul Centrifuges The encoded protein is the

The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage

ADP-ribosylation is a reversible posttranslational modification used to regulate protein function

suggesting a role in regulating insulin sensitivity

stabilizes p53/TP53 by affecting its interaction with ubiquitin ligase MDM2 (PubMed: 25732823)

EpoR(Phospho Tyr426) Polyclonal Antibody, 20ul Centrifuges The encoded protein is theThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce