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MMP-8 Polyclonal Antibody, 50ul Primary Antibodies The encoded protein has been

SKU: 37999070278

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MMP-8 Polyclonal Antibody, 50ul Primary Antibodies The encoded protein has beenMMP8 encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N termini. This protein functions in the degradation of type I, II

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Description

The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID: 18057535) and regulated by p53 (PMID: 19602589)

both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters

|induction:Regulated by cellular iron levels through binding of the iron regulatory proteins| IRP1 and IRP2| to iron-responsive elements in the 3'-UTR

delta opioid receptor (OPRD1)

MMP-8 Polyclonal Antibody, 50ul Primary Antibodies The encoded protein has beenMMP8 encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N termini. This protein functions in the degradation of type I, II

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