GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence Required for stabilization of KCNH1

Required for stabilization of KCNH1 channels at the cell membrane (PubMed: 23144454)

This gene is located 7 kb telomeric to gene family member ABCB2

The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease| Yme1p

It has both 17alpha-hydroxylase and 17

GFAP Monoclonal Antibody(5C8), 50ul Cell Senescence Required for stabilization of KCNH1This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.