Rat Interleukin 18, IL-18 ELISA Kit, 96T Digital Burette |Contains 1 PID domain

|Contains 1 PID domain

The encoded protein was originally described in bile ducts of liver as biliary glycoprotein

Regulates remodeling of the extracellular matrix by up-regulation of the Matrix Metalloproteinases MMP2

PubMed: 19960512)

Rat Interleukin 18, IL-18 ELISA Kit, 96T Digital Burette |Contains 1 PID domainA proinflammatory cytokine primarily involved in polarized T helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF kappa B, triggering synthesis of inflammatory mediators. Synergizes with IL12 interleukin 12 to induce IFNG synthesis from T helper 1 (Th1) cells and natural killer (NK) cells.