Human Grb2-associated-binding Protein 2, GAB2 ELISA Kit, 96T Plasma genotoxin-activated checkpoint complex that is

genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage

Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation (PubMed: 18439902)

providing reliable experimental results with consistency

Binds to CCR9

Human Grb2-associated-binding Protein 2, GAB2 ELISA Kit, 96T Plasma genotoxin-activated checkpoint complex that isAdapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI 3 kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.