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IP-10 Polyclonal Antibody, 100ul Antibodies Multiple alternately spliced transcript variants

SKU: 38569953008

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IP-10 Polyclonal Antibody, 100ul Antibodies Multiple alternately spliced transcript variantsThis antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T cell migration, and modulation of adhesion molecule expression.

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Description

Multiple alternately spliced transcript variants which encode different protein isoforms have been described

This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1

It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units

which mediates transport to and from the nucleus

IP-10 Polyclonal Antibody, 100ul Antibodies Multiple alternately spliced transcript variantsThis antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T cell migration, and modulation of adhesion molecule expression.

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