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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and also as a coactivator

SKU: 38622778696

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SEK85.00 SEK134.00

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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and also as a coactivatorThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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Description

and also as a coactivator of NF-kappaB-mediated transcription

RAF1 and IRS1 proteins

and overexpressed in colon tumors

It may contribute to the repression of target genes of the Wnt signaling pathway

CLCN5 Polyclonal Antibody, 20ul Vortex Mixer and also as a coactivatorThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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