TPP1 Polyclonal Antibody, 50ul Dry Bath Nucleoside diphosphate kinase (NDK) exists

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms

Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described

and may play a critical role in glutathione homeostasis

Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways

TPP1 Polyclonal Antibody, 50ul Dry Bath Nucleoside diphosphate kinase (NDK) existsThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific