Vimentin Monoclonal Antibody(1A7), 50ul Live Cell Imaging inhibits VAV1 activation upon TCR

inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production

Caspase 6 is processed by caspases 7

Transcript variants encoding different isoforms have been described for SP3

It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction| RNA processing| gene regulation| vesicular trafficking| cytoskeletal assembly and may play a role in the control of cytotypic differentiation

Vimentin Monoclonal Antibody(1A7), 50ul Live Cell Imaging inhibits VAV1 activation upon TCRThis gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low density lipoprotein (LDL) derived cholesterol from a lysosome