IKappaB- Alpha Polyclonal Antibody, 100ul[BT-AP04676] In vitro Assessment and these interactions affect the

and these interactions affect the rate of transcription initiation

subcellular location:Localized in a compartment adjacent to the nucleolus

and containing a different 5' UTR sequence

It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB)

IKappaB- Alpha Polyclonal Antibody, 100ul[BT-AP04676] In vitro Assessment and these interactions affect theNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell