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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences 2002 [PubMed 11784320])
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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences 2002 [PubMed 11784320])AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with
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