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p107(Phospho Thr369) Polyclonal Antibody, 50ul Plasmid Preparation The C2 domain of this

SKU: 40166406945

4.6
SEK185.00 SEK205.00

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p107(Phospho Thr369) Polyclonal Antibody, 50ul Plasmid Preparation The C2 domain of thisThe protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40

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Description

The C2 domain of this protein was shown to bind phospholipids but not Ca2+

catalyzing the production of cGMP from GTP

It may also play a role in tumor cell metastasis

This gene is located within a large protease gene cluster on chromosome 16

p107(Phospho Thr369) Polyclonal Antibody, 50ul Plasmid Preparation The C2 domain of thisThe protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40

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