TBCD7 Rabbit Polyclonal Antibody, 100ul Centrifuges This transmembrane protein localizes to

This transmembrane protein localizes to the endoplasmic reticulum of many tissues

Exon 1 encodes the leader peptide| exons 2 and 3 encode the two extracellular domains| exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

MDM2 is itself transcriptionally-regulated by p53

Favors Hoogsteen base-pairing in the active site

TBCD7 Rabbit Polyclonal Antibody, 100ul Centrifuges This transmembrane protein localizes toThis gene encodes a member of the TBC domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1 TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus