TM11D Polyclonal Antibody, 100ul Gel & Buffers The encoded preproprotein is secreted

The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease

SMG7 encodes protein SMG7 that is essential for nonsense-mediated mRNA decay (NMD)

A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology

The genomic organization of this gene

TM11D Polyclonal Antibody, 100ul Gel & Buffers The encoded preproprotein is secretedThis gene encodes a trypsin like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29 38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane