CHOP(Phospho Ser30) Polyclonal Antibody, 50ul Custom Peptide Synthesis TGFBR2 encodes a member of

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

Multiple phosphorylation sites have been identified: ser297 and Ser392 mediate 14-3-3 binding

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

CHOP(Phospho Ser30) Polyclonal Antibody, 50ul Custom Peptide Synthesis TGFBR2 encodes a member ofThis gene encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. The protein functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene