ATRX Polyclonal Antibody, 50ul Thermo Mix Histone deacetylase 5 encoded by

Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family

a chromodomain typical of proteins which bind histones

Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis

Enhances androgen receptor-mediated transcription

ATRX Polyclonal Antibody, 50ul Thermo Mix Histone deacetylase 5 encoded byThe protein encoded by ATRX (ATRX, chromatin remodeler) contains an ATPase helicase domain, and thus it belongs to the SWI SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in ATRX are associated with an X