OREX Polyclonal Antibody, 100ul RNA Synthesis Defects in this gene are

Defects in this gene are associated with isolated cleft palate and mental retardation

Transcript variants encoding different isoforms have been described for this gene

The other two isoforms

This gene has a partial pseudogene on chromosome 1

OREX Polyclonal Antibody, 100ul RNA Synthesis Defects in this gene areThis gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.