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GCH1 Polyclonal Antibody, 100ul Reservoirs KHSRP encodes a multifunctional RNA-binding

SKU: 41131063908

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GCH1 Polyclonal Antibody, 100ul Reservoirs KHSRP encodes a multifunctional RNA-bindingThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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Description

KHSRP encodes a multifunctional RNA-binding protein

Several transcript variants encoding different isoforms have been found for CLIP1

help mediate attachment and may also participate in regulating dynein activity

It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid

GCH1 Polyclonal Antibody, 100ul Reservoirs KHSRP encodes a multifunctional RNA-bindingThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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