CD6 Polyclonal Antibody, 100ul[BT-AP02235] DNA Synthesis The protein encoded by this

The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts

forms laminin-5

Alternative splicing results in transcript variants

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CD6 Polyclonal Antibody, 100ul[BT-AP02235] DNA Synthesis The protein encoded by thisCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.