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AP-1/Jun D Polyclonal Antibody, 50ul Protein Expression The zinc finger protein SNAI1

SKU: 42707857720

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AP-1/Jun D Polyclonal Antibody, 50ul Protein Expression The zinc finger protein SNAI1JUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

The zinc finger protein SNAI1 encoded by SNAI1 is structurally similar to the Drosophila snail protein

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells

When bound to KRT17| regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway

May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production

AP-1/Jun D Polyclonal Antibody, 50ul Protein Expression The zinc finger protein SNAI1JUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein (Jun proto oncogene, AP 1 transcription factor subunit) which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. JUN is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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