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IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 50ul Inoculating Loops/Needles This protein may be important

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IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 50ul Inoculating Loops/Needles This protein may be importantThis gene encodes a member of the serine threonine protein kinase family. The encoded protein a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway thereby activating the transcription factor.

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Description

This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3

The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins

mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis

The product of CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways

IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 50ul Inoculating Loops/Needles This protein may be importantThis gene encodes a member of the serine threonine protein kinase family. The encoded protein a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway thereby activating the transcription factor.

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