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OAS2 Polyclonal Antibody, 50ul Dialysis Mutations in this gene are

SKU: 43417762058

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SEK185.00 SEK225.00

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OAS2 Polyclonal Antibody, 50ul Dialysis Mutations in this gene areOAS2 encodes a member of the 2 5A synthetase family, essential proteins involved in the innate immune response to viral infection. The 2' 5' oligoadenylate synthetase 2 is induced by interferons and uses adenosine triphosphate in 2' specific nucleotidyl transfer reactions to synthesize 2',5' oligoadenylates (2 5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known

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Description

Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10)

and it may contribute to the antiviral activity of CD8 (+) T-cells

their full-length nature has not been determined

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain| a DHR-2 (CZH-2) domain and an SH3 domain

OAS2 Polyclonal Antibody, 50ul Dialysis Mutations in this gene areOAS2 encodes a member of the 2 5A synthetase family, essential proteins involved in the innate immune response to viral infection. The 2' 5' oligoadenylate synthetase 2 is induced by interferons and uses adenosine triphosphate in 2' specific nucleotidyl transfer reactions to synthesize 2',5' oligoadenylates (2 5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known

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