SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging Alterations in this region have

Alterations in this region have been associated with the Beckwith-Wiedemann syndrome

is not inhibited by warfarin

This gene is broadly expressed

This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development

SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging Alterations in this region haveThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced