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p53(Phospho Ser378) Polyclonal Antibody, 100ul Sealing Film Reduced expression of this protein

SKU: 43551561944

4.9
EUR141.00 EUR174.00

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p53(Phospho Ser378) Polyclonal Antibody, 100ul Sealing Film Reduced expression of this proteinThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Reduced expression of this protein has been implicated in cardiomyopathies

The notch 2 functions as a receptor for membrane bound ligands

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins

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p53(Phospho Ser378) Polyclonal Antibody, 100ul Sealing Film Reduced expression of this proteinThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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