SH2B3 Polyclonal Antibody, 50ul Buffer Solutions High affinity receptor for urotensin-2

High affinity receptor for urotensin-2 and urotensin-2B

and may be involved in pancreatic lithogenesis

The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily

Type I and II receptors form a stable complex after ligand binding| resulting in phosphorylation of type I receptors by type II receptors

SH2B3 Polyclonal Antibody, 50ul Buffer Solutions High affinity receptor for urotensin-2This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced