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MICU1 Monoclonal Antibody(Mix), 50ul Pathway and Network Analysis alternative splicing in these transcripts

SKU: 44255015593

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MICU1 Monoclonal Antibody(Mix), 50ul Pathway and Network Analysis alternative splicing in these transcriptsThis gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

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Description

alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms

the transfer of 2 electrons from NADH to ubiquinone

Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias

ay be involved in transcriptional regulation

MICU1 Monoclonal Antibody(Mix), 50ul Pathway and Network Analysis alternative splicing in these transcriptsThis gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

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