JIP4 Polyclonal Antibody, 100ul Digital Burette Members of this subfamily are

Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains| and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

Two homotrimeric forms of type XVII collagen exist

spanning 180 kb and consisting of 67 exons

JIP4 Polyclonal Antibody, 100ul Digital Burette Members of this subfamily areThis gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen activated protein kinases and mediates c Jun terminal kinase signaling. This protein also binds to kinesin 1 and may be involved in microtubule based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.