PLC gamma1(Phospho Tyr783) Polyclonal Antibody, 20ul Cell Biology NSF is required for general

NSF is required for general membrane transport and trafficking

It may play a role in tumor cell metastasis

Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia

In one family with congenital myasthenic syndrome affecting limb-girdle muscles| a mutation in this gene was found

PLC gamma1(Phospho Tyr783) Polyclonal Antibody, 20ul Cell Biology NSF is required for generalThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it