RAP1B Polyclonal Antibody, 100ul Bio-Reaction Tube The N-terminus is poorly conserved

The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family

The protein functions in cap-independent translation of ornithine decarboxylase mRNA

This gene is activated by two G-protein alpha subunits

Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias

RAP1B Polyclonal Antibody, 100ul Bio-Reaction Tube The N-terminus is poorly conservedThis gene encodes a member of the RAS like small GTP binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin mediated cell signaling. This protein also plays a role in regulating outside in signaling in platelets. Alternate splicing results in multiple transcript variants.