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Akt Polyclonal Antibody, 50ul[BT-AP00338] Centrifugal Filter Mutations in this gene cause

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Akt Polyclonal Antibody, 50ul[BT-AP00338] Centrifugal Filter Mutations in this gene causeThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Mutations in this gene cause atrial septal defect with atrioventricular conduction defect

Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor

As shown for the yeast homolog| which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases| this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors

Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors

Akt Polyclonal Antibody, 50ul[BT-AP00338] Centrifugal Filter Mutations in this gene causeThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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