AIRE-1 Polyclonal Antibody, 20ul[BT-AP00311] Purification such as fatal cardiac arrhythmias

such as fatal cardiac arrhythmias and hereditary spherocytosis

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AIRE-1 Polyclonal Antibody, 20ul[BT-AP00311] Purification such as fatal cardiac arrhythmiasAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and