Smad3 Polyclonal Antibody, 50ul[BT-AP08390] Sampling Tubes Members of this family are

Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal

which has over 46

tissue specificity:Expressed in most tissues

and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome

Smad3 Polyclonal Antibody, 50ul[BT-AP08390] Sampling Tubes Members of this family areMothers against decapentaplegic homolog 3 encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a