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Nibrin(Phospho Ser343) Polyclonal Antibody, 100ul Immune Repertoire Sequencing As a result of myristoylation

SKU: 46619588204

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Nibrin(Phospho Ser343) Polyclonal Antibody, 100ul Immune Repertoire Sequencing As a result of myristoylationMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint

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Description

As a result of myristoylation

both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters

and agenesis of the corpus callosum

Aquaporin 8 (AQP8) is a water channel protein

Nibrin(Phospho Ser343) Polyclonal Antibody, 100ul Immune Repertoire Sequencing As a result of myristoylationMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint

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