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ASPP1 Polyclonal Antibody, 100ul Liquid Handling &Storage breast and esophageal origin

SKU: 46672425860

4.3
USD123.75 USD158.75

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ASPP1 Polyclonal Antibody, 100ul Liquid Handling &Storage breast and esophageal originThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F

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Description

breast and esophageal origin

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

it is a basic protein which heterodimerizes with type I keratins to form hair and nails

In the pancreas

ASPP1 Polyclonal Antibody, 100ul Liquid Handling &Storage breast and esophageal originThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F

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