Smad3 Polyclonal Antibody, 20ul[BT-AP08387] Proteases part of the immunoglobulin superfamily

part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2

Inherited mutations in BRCA1 and this gene

Smad3 Polyclonal Antibody, 20ul[BT-AP08387] Proteases part of the immunoglobulin superfamilyMothers against decapentaplegic homolog 3 encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a