Rat Interleukin 33, IL-33 ELISA Kit, 96T Miscellaneous Involved in immune regulation

Involved in immune regulation

This protein may be involved in tumor suppression

controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance (PubMed: 11875044

Seems to be involved in early and late stages of mammalian cardiovascular development

Rat Interleukin 33, IL-33 ELISA Kit, 96T Miscellaneous Involved in immune regulationCytokine that binds to and signals through the IL1RL1 ST2 receptor which in turn activates NF kappa B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T helper type 2 associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses