I-TAC Rabbit Polyclonal Antibody, 20ul Sampling Tubes Two similar genes are located

Two similar genes are located nearby on chromosome 7q22 and a pseudogene is found on chromosome 7p13

homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family

conferring protection against severe malaria

I-TAC Rabbit Polyclonal Antibody, 20ul Sampling Tubes Two similar genes are locateddisease: Expressed in a variety of skin disorders including allergic contact dermatitis lichen planus and mycosis fungoides. Chemotactic for interleukin activated T cells but not unstimulated T cells neutrophils or monocytes. Induces calcium release in activated T cells. Binds to CXCR3. May play an important role in CNS diseases which involve T cell recruitment. May play a role in skin immune responses. induction: By interferon gamma and interferon