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PLOD2 Polyclonal Antibody, 100ul Supplements This protein may have proton-sensing

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PLOD2 Polyclonal Antibody, 100ul Supplements This protein may have proton-sensingThe protein encoded by this gene is a membrane bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers Danlos syndrome

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Description

This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids

The protein is expressed in the photoreceptor layer of the retina| and the gene is mutated in autosomal recessive retinitis pigmentosa

This cytokine is expressed in carcinoma cell lines

The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections

PLOD2 Polyclonal Antibody, 100ul Supplements This protein may have proton-sensingThe protein encoded by this gene is a membrane bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers Danlos syndrome

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