Nephrin Polyclonal Antibody, 100ul Tubes Both subunits are members of

Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160)

The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor

this protein may play a role in metal homeostasis

CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere

Nephrin Polyclonal Antibody, 100ul Tubes Both subunits are members ofNPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type 1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this