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SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 50ul Dry Bath Other AID/APOBEC family members are

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SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 50ul Dry Bath Other AID/APOBEC family members areThis gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b together with splicing factor 3a and a 12S RNA unit forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b 3a complex binds pre mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre mRNA. Splicing factor 3b is also a component of the minor U12 type spliceosome. The

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Description

Other AID/APOBEC family members are involved in mRNA editing

subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine

The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 50ul Dry Bath Other AID/APOBEC family members areThis gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b together with splicing factor 3a and a 12S RNA unit forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b 3a complex binds pre mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre mRNA. Splicing factor 3b is also a component of the minor U12 type spliceosome. The

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