Rabbit Interleukin 4, IL-4 ELISA Kit, 96T Inoculating Loops/Needles SRSF11 (serine and arginine rich

SRSF11 (serine and arginine rich splicing factor 11) encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors

SURF1 encodes surfeit locus protein 1 localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex

The enzyme hormone is secreted by the kidney

Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA

Rabbit Interleukin 4, IL-4 ELISA Kit, 96T Inoculating Loops/Needles SRSF11 (serine and arginine richParticipates in at least several B cell activation processes as well as of other cell types. It is a costimulator of DNA synthesis. It induces the expression of class II MHC molecules on resting B cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.