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Histone H4 Polyclonal Antibody, 100ul[BT-AP04122] Enzymes A mutation in this gene

SKU: 48448668937

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Histone H4 Polyclonal Antibody, 100ul[BT-AP04122] Enzymes A mutation in this geneHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin

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Description

A mutation in this gene results in somatostatin analog resistance

in the presence of NADPH

GO annotations related to this gene include protein homodimerization activity and extracellular matrix binding

Under hypoxic conditions activates the transcription of over 40 genes| including| erythropoietin| glucose transporters| glycolytic enzymes| vascular endothelial growth factor| and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia

Histone H4 Polyclonal Antibody, 100ul[BT-AP04122] Enzymes A mutation in this geneHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin

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