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SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Patients with defects in this

SKU: 48471624285

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SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Patients with defects in thisThis gene encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols

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Description

Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections

Mammals have three related thioredoxin reductases

The 9 aa bradykinin peptide elicits many responses including vasodilation

Himmelfarb et al

SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Patients with defects in thisThis gene encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols

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