Rev-erb alpha(Phospho-Ser55/59) Rabbit Polyclonal Antibody, 50ul Immunology Two alternately spliced transcripts encoding

Two alternately spliced transcripts encoding two protein isoforms have been identified

Mutations in this gene are associated with multiple epiphyseal dysplasia

and endoplasmic reticulum stress-associated protein degradation

which coordinate zinc finger binding and are characterized by three cysteine residues and one histidine residue

Rev-erb alpha(Phospho-Ser55/59) Rabbit Polyclonal Antibody, 50ul Immunology Two alternately spliced transcripts encodingThis gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic