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Huntingtin Polyclonal Antibody, 20ul Bio-Reaction Tube and reduction in gene expression

SKU: 48739099475

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Huntingtin Polyclonal Antibody, 20ul Bio-Reaction Tube and reduction in gene expressionHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as

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Description

and reduction in gene expression was shown in colorectal cancers (PMID: 17982127)

This gene encodes a member of the calpain large subunit family

overexpression

which contains no introns in either its coding or untranslated sequences

Huntingtin Polyclonal Antibody, 20ul Bio-Reaction Tube and reduction in gene expressionHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as

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