MDMX Monoclonal Antibody, 50ul Protein Analysis MRPL11 is a nuclear gene

MRPL11 is a nuclear gene encodes a 39S subunit component of the mitochondial ribosome

Complex II of the respiratory chain

RPL15 (ribosomal protein L15) encodes a ribosomal protein that is a component of the 60S subunit

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MDMX Monoclonal Antibody, 50ul Protein Analysis MRPL11 is a nuclear geneThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation