CHD8 Polyclonal Antibody, 20ul Hepatocytes The PCAF histone acetylase complex

The PCAF histone acetylase complex

It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP

and the full-length nature of two of them has been reported

and thus may function as a regulator of Rho signaling pathways

CHD8 Polyclonal Antibody, 20ul Hepatocytes The PCAF histone acetylase complexThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.