Beclin-1 Polyclonal Antibody, 100ul[BT-AP14447] Miscellaneous This protein functions as a

This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines

It is expressed only in brain and ovary

similarity:Contains 1 AGC-kinase C-terminal domain

The enzyme is found in nearly all cells capable of oxidative metablism

Beclin-1 Polyclonal Antibody, 100ul[BT-AP14447] Miscellaneous This protein functions as aThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.