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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Additional variants have been found

SKU: 51184121610

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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Additional variants have been foundEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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Description

Additional variants have been found but their full-length nature has not been determined

Three transcript variants encoding two different proteins have been found for this gene

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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Additional variants have been foundEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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